PReS-FINAL-2243: Reduced volumetric trabecular bone mineral density in children with idiopathic hypercalciuria. A peripheral quantitative computed tomography (PQCT) study (preliminary results)

Methods We studied 14 children (8 boys6 girls, aged 6-18 years) with newly discovered IH who were admitted to our clinic. Most of them presented with either hematuria or recurrent abdominal or lumbar pain. After establishment of the diagnosis, all children underwent DXA of the lumbar spine. We also performed pQCT of the tibia (Stratec XCT-2000 scanner), 4 slices were obtained at the 4%, 14%, 38% and 66% of tibia length sites. For the 4% slice, we assessed variables of trabecular bone and especially trabecular BMD (TRAB_DEN, mg/cm). For 14% we assessed parameters of subcortical bone and for the 38% and 66% sites parameters of cortical bone. pQCT data of the children with IH were compared to those of healthy race-, ageand sex-matched children from the published pQCT database of Moyer-Miller et al (J Clin Densitom, 2008) who used the same pQCT device, software and site measurements as we did.